Novel manufacturing process design enables hotlab manufacturing scale-up

20 OCTOBER 2020, DEVENTER – Today a first clinical QuiremSpheres™ patient procedure took place with a patient dose prepared using a novel hotlab manufacturing process design, developed together with VANDERWILT Techniques. The new process improves radiation safety for the hotlab operators and limits the production time, preparing for further scaling-up of the production of QuiremScout™ and QuiremSpheres™. QuiremScout™ is an innovative product for screening liver cancer patients before they are treated with QuiremSpheres™. QuiremSpheres™ is a CE-marked medical device indicated for treatment of unresectable liver tumors.

“Quirem Medical and VANDERWILT Techniques have a long-standing strategic partnership during which VANDERWILT has proven to be instrumental in the optimization of the hotlab processing steps. The effectuation of this latest process innovation, including bespoke instruments and tooling, is a new milestone. It supports our hotlab operators in their daily operations, minimizing processing time while reducing dose exposure significantly.” says Stuart Koelewijn, Hotlab Operations Manager of Quirem Medical BV.

“We see a strongly increasing demand for our products throughout Europe and beyond. VANDERWILT has proven to be a reliable and innovative partner to us, while we are constantly improving our internal processes to match the increasing demand and to prepare for the global expansion of our business.”  says Jan Sigger, CEO of Quirem Medical BV.

About Quirem Medical

Quirem Medical is a spin-off company from the University Medical Center in Utrecht with a mission to develop and manufacture the next generation microspheres for targeted interventional treatment of liver tumors. Its innovative Holmium-166 platform technology provides physicians a complete CE-marked SIRT solution including QuiremScout™, QuiremSpheres™ and the supporting dosimetry software Q-Suite™. The company is based in Deventer, the Netherlands and has approximately 30 employees. As of July 2020, Quirem Medical is a wholly owned subsidiary of Terumo, a global leader in medical technology based in Tokyo, Japan.

About VANDERWILT techniques

VANDERWILT Techniques is a development and manufacturing company, specialized in products for nuclear medicine such as manual dispensing and shielding products, QA-phantoms and patient positioning accessories. VANDERWILT Techniques is based in Boxtel, the Netherlands. For more information, see

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