Creating clinical value through meaningful innovation
Our company
At Quirem Medical we believe treatment outcome of unresectable liver cancer with SIRT can be improved by using microspheres that can be visualized and quantified to improve patient selection, planning and treatment verification. Will you join us in developing and commercializing the next-generation SIRT microspheres?
Management Team

Jan Sigger
Founder
Chief Executive Officer
Jan Sigger held senior management positions at Royal Dutch Shell and Akzo Nobel before joining Nucletron, the global market leader in brachytherapy as CFO in 2008. Between 2008 – 2012 he was instrumental in transforming Nucletron into the fastest growing radiotherapy company and managed the sale from private equity ownership to Elekta AB in 2011. Jan Sigger is a Master in Business Economics and holds a post-graduate degree as Chartered Accountant.

Frank Nijsen
Co-Founder
Chief Scientific Officer
Frank Nijsen has performed research into Holmium microspheres for more than 20 years. He has led the successful valorisation of the Holmium technology and was instrumental in the creation of the spin-off company Quirem Medical. He holds as inventor many patents in the field. Frank Nijsen holds a doctorate in Medical Biology and is currently Associate Professor at the Radboud University Medical Center.
Supervisory Board

Peter Coenen
Member of the Board
Peter Coenen has more than 25 years of experience in the medical device area leading and adapting organizations to new market situations to deliver value to customers and the companies he worked for. Peter started his career in the medical device division of Ely Lilly which then became Guidant. After the acquisition of Guidant by Boston Scientific Peter was responsible for the legal merger of Guidant and BSX in Japan. He today is a Director and Board member in Terumo Europe responsible for the EMEA region as President of the Interventional business unit.

Tim Irish
Chairman
Tim Irish has worked in the life sciences industry for thirty years. His career has spanned global health technology companies across Europe and North America, including GSK, GE and Philips. Tim’s current governance portfolio covers Life Sciences, Healthcare and Education, both public and private, including Board roles as Senior Independent Director and NED at National Institute for Health and Care Excellence (NICE), various European MedTech Supervisory Board roles, and Professor of Practice at King’s College London’s School of Management and Business.

Paul Roos
Member of the Board
Paul Roos is a seasoned executive with extensive experience and a proven track record in the international life sciences industry, having spent over 10 years working in investment banking and over five years as a CFO. He currently serves as CFO of Polyganics. Previously Mr. Roos served as CFO of IRX Innovations and as CFO of Synthon. He began his career at the Corporate Finance Division of Kempen & Co, where he his final position was Executive Director in the Life Sciences/ Healthcare team.
Meet the Quirem team





Prior to joining Quirem Medical as Medical Director, Rijk worked at Philips within the Clinical Science department in the Image Guided Therapies division. There he was responsible for clinical evaluations of the supporting software medical devices. Before that, Rijk gained significant experience in designing and conducting clinical trials at Medtronic as a senior Clinical Research Specialist. He has a background in Biomedical Engineering (BSc and MSc), obtained at the University of Twente.
Before joining Quirem Medical as a product manager, Sander worked with Elekta, a global company creating solutions for treating cancer and brain disorders. Before that Sander worked as Medical Physicist Resident at the Erasmus MC. He has a MSc. degree in Biomedical Engineering and an BSc. degree in Applied Physics, both obtained at the Delft Technical University.
Before joining Quirem Medical as Company Secretary, Anneke worked with Avantor Performance Materials, a global supplier of ultrahigh purity life sciences materials for the pharmaceutical industry. She was Management Assistant working for the Management Team. Before that she worked as a Secretary with Recticel Bedding, a company that develops and makes boxsprings and mattresses. Anneke obtained a college diploma as a Management Assistant.
Before joining Quirem Medical Matthijs worked for Avantor Peformance Materials performing quality control on diagnostics hematological reagents. Apart from having a knack for technology Matthijs also was a member and head of the works council. After joining the Quirem Team Matthijs helped set up production and QC Operations. He currently manages the cold microsphere production team and patient dose logistics.
Before joining Quirem Medial as R&D Scientist Carla worked with Avantor Performance Materials, a global supplier of ultra-high purity life sciences materials for the pharmaceutical industry. There she worked in the R&D department, giving application support to pharmaceutical industry for all chemicals needed in the production of biomedicines. Before that Carla worked as R&D Analyst at the Radboud University Nijmegen. She has a BSc degree in Biochemistry, obtained at Saxion Hogeschool IJsselland.
Having a background in Mechanical Engineering (BEng) and Biomedical Engineering (MSc), Gerhard has a role to support the Quirem team in technical challenges in order to improve the processes for the production of QuiremSpheres.
Before joining Quirem Medical in 2015 as a Finance Manager, Anet worked with Avantor Performance Materials, a global supplier for the pharmaceutical industry. There she worked in the Finance & Salary Department for 15 years. She has a Bachelor of Economics degree obtained at Hogeschool Arnhem.
Before joining Quirem Medical Ilona obtained a BSc degree in Biochemistry at Saxion Hogeschool. During her graduation assignment she worked on a biomolecular research project into mammary gland tumors of the dog.
John joined Quirem in 2015 and is responsible for quality assurance as well as regulatory affairs. Through his 30 years of experience in quality assurance and quality management functions at Fuji Photo Film BV and Avantor Materials BV, he gained a broad knowledge of Japanese, cGMP and ISO 13485 quality management systems. John holds a doctor’s degree in chemistry and physics.
Véronique graduated as a Chemical/Physical Analyst in 2014. After graduating she stayed at Ausnutria Hyproca Analytics. Véronique worked as a Chemical/Physical Analyst until december 2016 and did research on baby food. In January 2017 Véronique joined Quirem Medical. Her job is the production of the Ho-microspheres and the Quality Control on the spheres.

Gerrit joined Quirem Medical from the very beginning to set-up imaging and software development activities at the company. He got involved in the holmium microsphere research during his PhD at the UMC Utrecht where his focus was on MRI based dosimetry of holmium radioembolization. He has a MSc. Degree in Applied Physics obtained at the University of Twente.
Stuart Koelewijn holds a bachelor in Biomedical Sciences and has performed research in the field of radionuclide therapy. One of the investigated strategies was to improve existing therapies by combining it with therapy based on holmium microspheres, now known as QuiremSpheres. At this moment, Stuart Koelewijn holds the position of Research Scientist in Chemistry and Radiobiology at Quirem Medical and continues the investigation to optimize treatment through radioembolization and in addition investigate the application of QuiremSpheres for treatment of cancers at various sites.
Having a background in Technical Medicine (BSc), Medical Imaging & Intervention (MSc) and Radiation Expertise level 3, all obtained at University Twente, Feiko has a role to support the Quirem team in imaging solutions for QuiremSpheres as well as training and support of customers.
Alinde joined the Quirem Medical team in January 2018 as QA/RA support officer. In this role she supports the QA manager and is, among other things, responsible for the document control system.
Before joining Quirem, Alinde worked for Avantor Performance Materials for 19 years, 3 years at the Quality Control department and 16 years at the QA department as QA/RA support officer. She also was an internal ISO-auditor and confidential adviser.
Fabiola joined the Quirem Medical team in May 2018 as a software tester. In this role, she is responsible for planning and conducting software testing activities at the company. Before joining Quirem, Fabiola worked for Suunto Oy for 12 years, 9 years as a test project manager coordinating testing of consumer electronics products and the last 3 years as data-analyst, collecting and analyzing software application data to understand application usage patterns and failures on the field.
Marloes obtained a BSc degree in Biochemistry at Saxion Hogeschool in 2013. After graduating, Marloes worked at “De Gezondheidsdienst voor Dieren”, Abbott Biologicals and Friesland Campina. In September 2018 Marloes joined Quirem Medcial as a Production & QC Chemist and is working on the production of the Ho-microspheres and the Quality Cotrol on the spheres.
Esther joined Quirem Medical in September 2018 as a project leader. In this role she works on automating and optimizing the Hot-lab production process of QuiremSpheres. Before that, Esther obtained a BSc degree in Chemistry at Saxion Hogeschool in Deventer.
José joined the Quirem Medical Team in September 2018 as a Project Leader. In this role she is dedicated to successfully finish a project. Before joining Quirem, José worked for the Rabobank for 15 years in many positions. The last position was Manager/Project Leader.
Before joining Quirem Medical as Logistics Coordinator Stephanie worked 8 years at Abbott, later on resulting in AbbVie, a global company in life saving & serving medicines. At AbbVie, she worked in several positions and multiple responsibilities gaining experience in Supply Chain Management, leading international projects and several tasks related to Process & Change Management. Because of her entrepreneurship as a Coach she trained and coached colleagues in procedures and work instructions all around the world. Stephanie has a Bachelor degree in Commerce – Communication obtained at Saxion Hogeschool Enschede.

Diana joined Quirem Medical in October 2018 as a member of the production team. Before that she has worked 28 years in an environmental laboratory, as a chemical analyst to analyse the pollution of soil, water and air samples.
Having a background in Technical Medicine (BSc) and Medical Imaging & Interventions (MSc) and a knowledge of radioactivity (level 3), all obtained at University Twente, Eline acts as a Clinical Support Officer within Quirem Medical. In that role she is engaged in supporting clinical research, developing clinical marketing materials, post-market surveillance and various other clinical aspects of QuiremSpheres®.
Having a background in Biomedical Engineering (BSc and MSc) with a specialization in Biotechnologies for Electronics, all obtained at Politecnico di Milano (Italy), Martina joined Quirem Medical as a Research Scientist. She has been recently funded by NWO, through the Industrial Doctorate program, to carry out her PhD at UMC Utrecht, in collaboration with Quirem Medical, aimed at introducing true personalized dosimetry into every day medical practice.